安井 弥前教授から

論文目録（1982-1999：英文原著のみ）

このページでは、教授就任前の安井 弥教授の論文業績を掲載しています。
教授就任後の論文業績については、研究のページの業績をご参照ください。

  1. Sumiyoshi H, Yasui W, Ochiai A and Tahara E: Effect of gastrin on tumor growth and cyclic nucleotide metabolism in xenotransplantable human gastric carcinoma in nude mice. Cancer Res 44:4276-4280, 1984
  2. Sumiyoshi H, Taniyama K, Ito H, Ochiai A, Yasui W and Tahara E: Secretory component and immunoglobulin in human gastric carcinoma: An immunohistochemical study. Jpn J Cancer Res 75:166-176, 1984
  3. Yasui W, Sumiyoshi H, Ochiai A, Yamahara M and Tahara E: Type I and II cyclic adenosine 3':5'-monophosphate-dependent protein kinase in human gastric mucosa and carcinomas. Cancer Res 45:1565-1568, 1985
  4. Yasui W and Tahara E: Effect of gastrin on gastric mucosal cyclic adenosine 3':5'-monophosphate- dependent protein kinase activity in rat stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine. Cancer Res 45:4763-4767, 1985（学位論文）
  5. Ochiai A, Yasui W and Tahara E: Growth-promoting effect of gastrin on human gastric carcinoma cell line TMK-1. Jpn J Cancer Res 76:1064-1071, 1985
  6. Yasui W, Sumiyoshi H, Ochiai A and Tahara E: Calcium-activated, phospholipid-dependent protein kinase in human gastric mucosa and carcinoma. Jpn J Cancer Res 76:1168-1173, 1985
  7. Yasui W, Sumiyoshi H, Ochiai A and Tahara E. Cholecystokinin inhibition of tumor growth and gastrin-stimulated cAMP metabolism in human gastric carcinoma in nude mice. Cancer Res 46:740-743, 1986
  8. Yasui W, Sumiyoshi H, Hata J, Mandai K and Tahara E: Gut endocrine cells in rat stomach carcinoma induced by N-methyl-N'-nitro-N-nitrosoguanidine. J Cancer Res Clin Oncol 111:87-92, 1986
  9. Tahara E, Sumiyoshi H, Hata J, Yasui W, Taniyama K, Hayashi T, Nagae S and Sakamoto S: Human epidermal growth factor in gastric carcinoma as a biologic marker of high malignancy. Jpn J Cancer Res 77:145-152, 1986
  10. Tahara E, Yasui W, Taniyama K, Ochiai A, Yamamoto T, Nakajo S and Yamamoto M. Ha-ras oncogene product in human gastric carcinoma: Correlation with invasiveness, metastasis or prognosis. Jpn J Cancer Res 77:517-522, 1986
  11. Kajihara H, Yasui W, Nakagawa H and Maeda Y: Light and electron microscopic observations of the white pulp of the dog spleen during hemorrhagic shock. Path Res Pract 181:586-595, 1986
  12. Sumiyoshi H, Kanezawa A, Yasui W and Tahara E: Effects of a protein-free diet on the rat stomach. Gastroenterol 92:1051-1059, 1987
  13. Yasui W, Sumiyoshi H, Yamamoto T, Oda N, Kameda T, Tanaka T and Tahara E: Expression of Ha-ras oncogene product in rat gastrointestinal carcinomas induced by chemical carcinogens. Acta Pathol Jpn 37:1731-1741, 1987
  14. Yamamoto T, Yasui W, Ochiai A, Ito H, Abe K, Yanaihara N and Tahara E: Immunohistochemical detection of c-myc-oncogene product in human gastric carcinomas: Expression in tumor cells and stromal cells. Jpn J Cancer Res 78:1169-1174, 1987
  15. Yasui W, Sumiyoshi H, Hata J, Kameda T, Ochiai A, Ito H and Tahara E: Expression of epidermal growth factor receptor in human gastric and colonic carcinomas. Cancer Res 48:137-141, 1988
  16. Yasui W, Hata J, Yokozaki H, Nakatani H, Ochiai A, Ito H and Tahara E: Interaction between epidermal growth factor and its receptor in progression of human gastric carcinoma. Int J Cancer 41:211-217, 1988
  17. Yamahara M, Fujito T, Shimosato T, Yokozaki H, Yasui W and Tahara E: Phenotypic expression of human epidermal growth factor in foetal submandibular gland and pleomorphic adenoma of salivary gland. Virchows Archiv A Pathol Anat 412:301-306, 1988
  18. Yasui W, Sumiyoshi H, Oda N, Miyamori S, Kameda T, Takekura N, Takanashi A and Tahara E: Interaction between epidermal growth factor and gastrin on DNA synthesis of the gastrointestinal mucosa in rats. Hiroshima J Med Sci 37:1-6, 1988
  19. Zuber M, Yasui W, Tan EM and Ryoji M: Quantitation and subcellular localization of proliferating cell nuclear antigen (PCNA/cyclin) on oocytes and eggs of Xenopus laevis. Exp Cell Res 182:384-393, 1989
  20. Yasui W and Ryoji M: Characterization of early DNA synthesis in Xenopus eggs after injection of circular plasmid DNA. Nucleic Acids Res 17:3709-3723, 1989
  21. Yasui W and Ryoji M: Presence of multiple species of polypeptides immunologically related to transcription factor TFIIIA in adult Xenopus tissues. Nucleic Acids Res 17:5597-5610, 1989
  22. Ryoji M, Tominna E and Yasui W: Minichromosome assembly accompanying repair-type DNA synthesis in Xenopus oocytes. Nucleic Acids Res 17:10243-10258, 1989
  23. Ochiai A, Yasui W, Kameda T, Takanashi A, Takekura N and Tahara E: Effect of phorbol esters on cell growth and epidermal growth factor receptor modulation in a human gastric carcinoma cell line TMK-1. Hiroshima J Med Sci 38:191-195, 1989
  24. Oda N. Tsujino T, Tsuda T, Yoshida K, Nakayama H, Yasui W and Tahara E: DNA ploidy pattern and amplification of ERBB and ERBB2 genes in human gastric carcinomas. Virchows Archiv B Cell Pathol 58:273-277, 1990
  25. Yasui W, Takekura N, Kameda T, Oda N, Ito M, Ito H and Tahara E: Effect of epidermal growth factor on rat stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine. Acta Pathol Jpn 40:165-171, 1990
  26. Takekura N, Yasui W, Yoshida K, Tsujino T, Nakayama H, Kameda T, Yokozaki H, Nishimura Y, Ito H and Tahara E: pp60c-src protein kinase activity in human gastric carcinomas. Int J Cancer 45:847-851, 1990
  27. Yoshida K, Tsujino T, Yasui W, Kameda T, Sano T, Nakayama H, Toge T and Tahara E: Induction of growth factor receptor and metalloproteinase genes by epidermal growth factor and/or transforming growth factor-α in human gastric carcinoma cell line MKN-28. Jpn J Cancer Res 81:793-798, 1990
  28. Ito M, Yoshida K, Kyo E, Ayhan A, Nakayama H, Yasui W, Ito H and Tahara E: Expression of several growth factors and their receptor genes in human colon carcinomas. Virchows Archiv B Cell Pathol 59:173-178, 1990
  29. Kameda T, Yasui W, Yoshida K, Tsujino T, Nakayama H, Ito M, Ito H and Tahara E: Expression of ERBB2 in human gastric carcinomas: Relationship between p185ERBB2 expression and the gene amplification. Cancer Res 50:8002-8009, 1990
  30. Ito H, Yasui W, Yoshida K, Nakayama H and Tahara E: Depressed tubular adenoma of the stomach: Pathological and immunohistochemical properties. Histopathology 17:419-426, 1990
  31. Takekura N, Yasui W, Kyo E, Yoshida K, Kameda T, Kitadai Y, Abe K, Umezawa K and Tahara E: Effect of tyrosine kinase inhibitor, erbstatin, on cell growth and growth factor/receptor expression in human gastric carcinoma cells. Int J Cancer 47:938-942, 1991
  32. Takanashi A, Yasui W, Yoshida K, Yokozaki H, Saito D, Abe K, Urakami K, Miki K and Tahara E: Inhibitory effect of 8-chloro-cyclic adenosine 3',5'-monophosphate on cell growth of gastric carcinoma cell lines. Jpn J Cancer Res 82:325-331, 1991
  33. Kajikawa K, Yasui W, Sumiyoshi H, Yoshida K, Nakayama H, Ayhan A, Yokozaki H, Ito H and Tahara E: Expression of epidermal growth factor in human tissues: Immunohistochemical and biochemical analysis. Virchows Archiv A Pathol Anat 418:27-32, 1991
  34. Kuniyasu K, Yoshida K, Yokozaki H, Yasui W, Ito H, Toge T, Ciardiello F, Persico MG, Saeki T, Salomon DS, Tahara E: Expression of cripto, a novel gene of the epidermal growth factor family, in human gastrointestinal carcinomas. Jpn J Cancer Res 82:969-973, 1991
  35. Tanimoto H, Yoshida K, Yokozaki H, Yasui W, Nakayama H, Ito H, Ohama K and Tahara E: Expression of basic fibroblast growth factor in human gastric carcinomas. Virchows Archiv B Cell Pathol 61:263-267, 1991
  36. Yasui W, Oda N, Ito H, Ichiba Y and Tahara E: Myxoid leiomyosarcoma of the stomach: A case report. Jpn J Clin Oncol 21:447-452, 1991
  37. Ito M, Yasui W, Kyo E, Yokozaki H, Nakayama H, Ito H and Tahara E: Growth inhibition of transforming growth factor β on human gastric carcinoma cells: Receptor and postreceptor signaling. Cancer Res 52:295-300, 1992
  38. Ito M, Yasui W, Nakayama H, Yokozaki H, Ito H and Tahara E: Reduced levels of transforming growth factor-beta type I receptor in human gastric carcinomas. Jpn J Cancer Res 83:86-92, 1992
  39. Kameda T, Yasui W, Tsujino T, Nakayama H, Ayhan A, Ito H and Tahara E: Tyrosine kinase activity of epidermal growth factor receptor in human gastric carcinomas. Path Res Pract 188:37-43, 1992
  40. Nishimura Y, Yasui W, Yoshida K, Matsuyama T, Dohi K and Tahara E: A serine protease inhibitor of benzamidine derivative inhibits the growth of human colon carcinoma cells. Jpn J Cancer Res 83:723-728, 1992
  41. Ayhan A, Yasui W, Yokozaki H, Ito H and Tahara E: Genetic abnormalities and expression of p53 in human colon carcinomas. Int J Oncol 1:431-437, 1992
  42. Mattar R, Yokozaki H, Yasui W, Ito H and Tahara E: p53 gene mutations in gastric cancer cell lines. Oncol (Life Sci Adv) 11:7-12, 1992
  43. Yokozaki H, Kuniyasu H, Kitadai Y, Nishimura K, Todo H, Ayhan A, Yasui W, Ito H and Tahara E: P53 point mutations in primary human gastric carcinomas. J Cancer Res Clin Oncol 119:67-70, 1992
  44. Yasui W, Ji Z-Q, Kuniyasu H, Ayhan A, Yokozaki H, Ito H and Tahara E: Expression of transforming growth factor alpha in human tissue: Immunohistochemical study and Northern blot analysis. Virchows Archiv A Pathol Anat 421:513-519, 1992
  45. Kuniyasu H, Yasui W, Kitadai Y, Yokozaki H, Ito H and Tahara E: Frequent amplification and expression of the c-met gene in human scirrhous type stomach cancer. Biochem Biophys Res Commun 189:227-232, 1992
  46. Kitadai Y, Yasui W, Yokozaki H, Kuniyasu H, Haruma K, Kajiyama G and Tahara E: The level of transcription factor Sp1 is correlated with the expression of EGF receptor in human gastric carcinomas. Biochem Biophys Res Commun 189:1342-1348, 1992
  47. Yasui W, Ayhan A, Kitadai Y, Nishimura K, Yokozaki H, Ito H and Tahara E: Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas. Int J Cancer 53:36-41, 1993
  48. Nakayama H, Yasui W, Yokozaki H and Tahara E: Reduced expression of nm23 is associated with metastasis of human gastric carcinomas. Jpn J Cancer Res 84:184-190, 1993
  49. Oda N, Yasui W, Ito H and Tahara E: Ossifying fibromyxoid tumor of soft parts: A case report. Jpn J Clin Oncol 23:64-68, 1993
  50. Kitadai Y, Yamazaki H, Yasui W, Kyo E, Yokozaki H, Kajiyama G, Johnson AC, Pastan I and Tahara E: GC factor represses transcription of several growth factor/receptor genes and causes growth inhibition of human gastric carcinoma cell lines. Cell Growth & Differ 4:291-296, 1993
  51. Yoshida K, Kuniyasu H, Yasui W, Kitadai Y, Toge T and Tahara E: Expression of growth factors and their receptors in human esophageal carcinomas: Regulation of expression by epidermal growth factor and transforming growth factor alpha. J Cancer Res Clin Oncol 119:401-407, 1993
  52. Ayhan A, Yasui W, Yokozaki H, Kitadai Y and Tahara E: Reduced expression of nm23 protein is associated with advanced tumor stage and distant metastases in human colorectal carcinomas. Virchows Archiv B Cell Pathol 63:213-218, 1993
  53. Yasui W, Sano T, Nishimura K, Kitadai Y, Ji Z-Q, Yokozaki H, Ito H and Tahara E: Expression of P-cadherin in gastric carcinomas and its reduction in tumor progression. Int J Cancer 54:49-52, 1993
  54. Yokozaki H, Ito M, Yasui W, Kyo E, Kuniyasu H, Kitadai Y, Tsubouchi H, Daikuhara Y and Tahara E: Biologic effect of hepatocyte growth factor on human gastric carcinoma cell lines. Int J Oncol 3:89-93, 1993
  55. Kuniyasu H, Yasui W, Yokozaki H, Kitadai Y and Tahara E: Aberrant expression of c-met mRNA in human gastric carcinomas. Int J Cancer 55: 72-75, 1993
  56. Kitadai Y, Yasui W, Yokozaki H, Kuniyasu H, Ayhan A, Haruma K, Kajiyama G, Johnson GR and Tahara E: Expression of amphiregulin, a novel gene of the epidermal growth factor family, in human gastric carcinomas. Jpn J Cancer Res 84:879-884, 1993
  57. Kyo E, Yokozaki H, Yanagihara K, Yasui W, Ito M, Sano T, Lee PS, Saya H and Tahara E: Reduced tumorigenicity and cell motility of a gastric carcinoma cell line by introduction of wild-type p53 gene. Int J Oncol 3:265-271, 1993
  58. Ito R, Kitadai Y, Kyo E, Yokozaki H, Yasui W, Yamashita U, Nikai H and Tahara E: IL-1alpha acts as an autocrine growth stimulator for human gastric carcinoma cells. Cancer Res 53:4102-4106, 1993
  59. Kochi K, Shigemoto S, Isono M, Maeda R, Shigemoto M, Yasui W and Matsuura Y: A case report of epithelioid leiomyosarcoma of transverse mesocolon: diagnosis and treatment. Hiroshima J Med Sci 42:125-128, 1993
  60. Miyazaki T, Kojima T, Yashiki M, Iwasaki Y, Wakamoto H, Taniguchi T and Yasui W: A case of death after trichloroethylene sniffing and a fight. Jpn J Forensic Toxicol 11:187-193, 1993
  61. Tsutsumi M, Yasui W, Naitoh A, Ohashi K, Kobayashi E, Noguchi O, Horiguchi K, Okita S, Tsujiuchi T, Ishikawa O, Konishi Y and Tahara E: Expression of cripto in human pancreatic tumors. Jpn J Cancer Res 85:118-121, 1994
  62. Lotan R, Ito H, Yasui W, Yokozaki H, Lotan D and Tahara E: Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas. Int J Cancer 56:474-480, 1994
  63. Kuniyasu H, Yasui W, Yokozaki H, Akagi M, Akama Y, Kitahara K, Fujii K and Tahara E: Frequent loss of heterozygosity of chromosome 7q is closely associated with progression of human gastric carcinomas. Int J Cancer 59:597-600, 1994
  64. Yoshida K, Kawami H, Kuniyasu H, Nishiyama M, Yasui W, Hirai T, Toge T and Tahara E: Coamplification of cyclin D, hst-1 and int-2 genes is a good biological marker of high malignancy for human esophageal carcinomas. Oncol Rep 1:493-496, 1994
  65. Ayhan A, Yasui W, Yokozaki H, Seto M, Ueda R and Tahara E: Alterations and expression of bcl-2 gene in human gastric and colonic carcinomas. Jpn J Cancer Res 85:584-591, 1994
  66. Kozako Y, Yasui W and Tahara E: Expression of b1 integrin in human gastric carcinomas: correlation with histological type and tumor progression. Int J Oncol 5:225-230, 1994
  67. Horii A, Han H-J, Shimada M, Yanagisawa A, Kato Y, Yasui W, Tahara E and Nakamura Y: Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers. Cancer Res 54:3373-3375, 1994
  68. Tannapfel A, Yasui W, Yokozaki H, Wittekind Ch and Tahara E: Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines. Virchows Archiv 425:139-144, 1994
  69. Kuniyasu H, Yasui W, Akama Y, Akagi M, Tohdo H, Ji Z-Q, Kitadai Y, Yokozaki H and Tahara E: Expression of cripto in human gastric carcinomas: an association with tumor stage and prognosis. J Exp Clin Cancer Res 13:151-157, 1994
  70. Yasui W, Kuniyasu H, Akama Y, Kitahara K, Nagafuchi A, Ishihara S, Tsukita S and Tahara E: Expression of E-cadherin, a- and b-catenins in human gastric carcinomas: correlation with histology and tumor progression. Oncol Rep 2:111-117, 1995
  71. Akagi M, Yokozaki H, Kitadai Y, Ito R, Yasui W, Haruma K, Kajiyama G and Tahara E: Expression of amphiregulin in human gastric cancer cell lines. Cancer 75S:1460-1466, 1995
  72. Fujii K, Yasui W, Shimamoto F, Yokozaki H, Nakayama H, Kajiyama G and Tahara E: Immunohistochemical analysis of nm23 gene product in human gallbladder carcinomas. Virchows Archiv 426:355-359, 1995
  73. Kitahara K, Yasui W, Kuniyasu H, Akama Y, Fujii K, Yokozaki H, Yunotani S, Hisatsugu T and Tahara E: Increased expression and phosphorylation of SH-PTP2 (SYP) in human gastric carcinomas. Oncol Rep 2:819-823, 1995
  74. Livingstone JI, Yasui W, Tahara E and Wastell C: Are Japanese and European gastric cancer the same biological entity? An immunohistochemical study. Br J Cancer 72:976-980, 1995
  75. Kitahara K, Yasui W, Kuniyasu H, Akama Y, Yokozaki H, Yunotani S, Hisatsugu T and Tahara E: Concurrent amplification of cyclin E and cdk2 genes in colorectal carcinomas. Int J Cancer 62:25-28, 1995
  76. Akama Y, Yasui W, Yokozaki H, Kuniyasu H, Kitahara K, Ishikawa T and Tahara E: Frequent amplification of the cyclin E gene in human gastric carcinomas. Jpn J Cancer Res 86:617-621, 1995
  77. Tahara H, Kuniyasu H, Yokozaki H, Yasui W, Shay JW, Ide T and Tahara E: Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions. Clin Cancer Res 1:1245-1251, 1995
  78. Kitahara K, Yasui W, Kuniyasu H, Yokozaki H, Fujii K, Hisatsugu T and Tahara E: Expression of Stat91, Ras-independent signal transducer and activator, in human gastric carcinomas. Int J Oncol 7:907-911, 1995
  79. Miyazaki T, Kojima T, Yashiki M, Iwasaki Y, Nagasawa N and Yasui W: A case of fetal epidural hematoma caused by a slight car collision and liability for the fatality. Res Pract Forens Med 38:231-234, 1995
  80. Kitahara K, Yasui W, Yokozaki H, Semba S, Hamamoto T, Hisatsugu T and Tahara E: Expression of cyclin D1, CDK4 and p27KIP1 is associated with the p16MTS1 gene status in human esophageal carcinoma cell lines. J Exp Therapeutics Oncol 1:7-12, 1996
  81. Semba S, Yokozaki H, Yamamoto S, Yasui W and Tahara E: Microsatellite instability in precancerous lesions and adenocarcinomas of the stomach. Cancer 77/8S:1620-1627, 1996
  82. Akagi M, Yasui W, Akama Y, Yokozaki H, Tahara H, Haruma K, Kajiyama G and Tahara E: Inhibition of cell growth by transforming growth factor b1 is associated with p53-independent induction of p21 in gastric carcinoma cells. Jpn J Cancer Res 87:377-384, 1996
  83. Fujii K, Yokozaki H, Yasui W, Kuniyasu H, Hirata M, Kajiyama G and Tahara E: High frequency of p53 gene mutations in adenocarcinomas of the gallbladder. Cancer Epidemiol Biomarkers Prev 5:461-466, 1996
  84. Yasui W, Akama Y, Kuniyasu H, Yokozaki H, Shimamoto F and Tahara E: Expression of cyclin E in human gastric adenomas and adenocarcinomas: Correlation with proliferative activity and p53 status. J Exp Therapeutics Oncol 1:88-94, 1996
  85. Akama Y, Yasui W, Kuniyasu H, Yokozaki H, Akagi M, Tahara H, Ishikawa T and Tahara E: No point mutations but a codon 31 polymorphism and decreased expression of p21SDI1/WAF1/CIP1/MDA6 gene in human gastric carcinomas. Mol Cell Differ 4:187-198, 1996
  86. Akama Y, Yasui W, Kuniyasu H, Yokozaki H, Akagi M, Tahara H, Ishikawa T and Tahara E: Genetic status and expression the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines. Jpn J Cancer Res 87:824-830, 1996
  87. Yasui W, Kuniyasu H, Yokozaki H, Semba S, Shimamoto F and Tahara E: Expression of cyclin E in colorectal adenomas and adenocarcinomas: Correlation with expression of Ki-67 antigen and p53 protein. Virchows Archiv 429:13-19, 1996
  88. Yasui W, Akama Y, Kuniyasu H, Yokozaki H, Semba S, Shimamoto F and Tahara E: Expression of cyclin-dependent kinase inhibitor p21WAF1/CIP1 in non-neoplastic mucosa and neoplasia of the stomach: Relation with p53 status and proliferative activity. J Pathol 180:122-128, 1996
  89. Fujii K, Yasui W, Kuniyasu H, Itoh M, Hanada K, Kajiyama G and Tahara E: Expression of cripto in human gall bladder lesions. J Pathol 180:166-168, 1996
  90. Kuniyasu H, Yasui W, Shimamoto F, Nakahara M, Asahara T, Dohi K and Tahara E: A case of hepatoblastoma in an adult associated with c-met proto-oncogene imbalance. Pathol Int 46:1005-1010, 1996
  91. Kuniyasu H, Yasui W, Kitahara K, Naka K, Yokozaki H, Akama Y, Hamamoto T, Tahara H and Tahara E: Growth-inhibitory effect of interferon-beta is associated with the induction of cyclin-dependent kinase inhibitor, p27KIP1 in a human gastric carcinoma cell line. Cell Growth & Differ 8:47-52, 1997
  92. Kuniyasu H, Domen T, Hamamoto T, Yokozaki H, Yasui W, Tahara H and Tahara E: Expression of human telomerase RNA is an early event of stomach carcinogenesis. Jpn J Cancer Res 88:103-107, 1997
  93. Yasui W, Akama Y, Yokozaki H, Semba S, Kudo Y, Shimamoto F and Tahara E: Expression of p21WAF1/CIP1 in colorectal adenomas and adenocarcinomas and its correlation with p53 protein expression. Pathol Int 47:470-477, 1997
  94. Ueda H, Imazu M, Hayashi Y, Ono K, Yasui W and Yamakido M: Comparison of proliferative activity in coronary plaques from patients with coronary ischemia -Histopathological and immunohistochemical analysis-. Hiroshima J Med Sci 46:31-42, 1997
  95. Ueda H, Imazu M, Hayashi Y, Ono K, Yasui W and Yamakido M: Immunohistochemical analysis of hepatocyte growth factor in human coronary atherectomy specimens: comparison with transforming growth factor-beta isoforms. Virchows Archiv 430:407-415, 1997
  96. Yasui W, Kudo Y, Semba S, Yokozaki H and Tahara E: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. Jpn J Cancer Res 88:625-629, 1997
  97. Abe S, Sasano H, Katoh K, Ohara S, Arikawa T, Noguchi T, Asaki S, Yasui W, Tahara E, Nagura H and Toyota T: Immunohistochemical studies on EGF family growth factors in normal and ulcerated human gastric mucosa. Digestive Diseases Sci 42:1199-1209, 1997
  98. Ito R, Yasui W, Yokozaki H, Yamashita U, Takata T, Nikai H and Tahara E: Growth stimulatory effect of interleukin (IL)-1a produced by oral squamous cell carcinoma cell lines. Int J Oncol 11:807-812, 1997
  99. Naka K, Yokozaki H, Domen T, Hayashi K, Kuniyasu H, Yasui W, Lotan R and Tahara E: Growth inhibition of cultured human gastric cancer cells by 9-cis-retinoic acid with induction of cdk inhibitor Waf1/Cip1/Sdi1/p21 protein. Differentiation 61:313-320, 1997
  100. Kudo Y, Yasui W, Ue T, Yamamoto S, Yokozaki H, Nikai H and Tahara E: Overexpression of CDK-activating CDC25B phosphatase in human gastric carcinomas. Jpn J Cancer Res 88:947-952, 1997
  101. Ito R, Yasui W, Kuniyasu H, Yokozaki H and Tahara E: Expression of IL-6 and its effect on the cell growth of gastric carcinoma cell lines. Jpn J Cancer Res 88:953-958, 1997
  102. Hamamoto T, Yokozaki H, Semba S, Yasui W, Yunotani S, Miyazaki K and Tahara E: Altered microsatellites in incomplete-type intestinal metaplasia adjacent to primary gastric cancers. J Clin Pathol 50:841-846, 1997
  103. Nakahara M, Yokozaki H, Yasui W, Dohi K and Tahara E: Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 genes in Japanese hereditary nonpolyposis colorectal cancer kindreds. Cancer Epidemiol Biomarkers Prev 6:1057-1064, 1997
  104. Kitadai Y, Haruma K, Sumii K, Yamamoto S, Ue T, Yokozaki H, Yasui W, Ohmoto Y, Kajiyama G, Fidler IJ and Tahara E: Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol 152:93-100, 1998
  105. Shitara Y, Yokozaki H, Yasui W, Takenoshita S, Nagamachi Y and Tahara E: Mutation of the transforming growth factor-b type II receptor gene is rare event in human gastric carcinomas. Int J Oncol 12:1061-1065, 1998
  106. Ue T, Yokozaki H, Kitadai Y, Yamamoto S, Yasui W, Ishikawa T and Tahara E: Co-expression of osteopontin and CD44v9 in gastric cancer. Int J Cancer 79:127-132, 1998
  107. Semba S, Yokozaki H, Yasui W and Tahara E: Frequent microsatellite instability and loss of heterozygosity in the region including BRCA1 (17q21) in young patients with gastric cancer. Int J Oncol 12:1245-1251, 1998
  108. Yasui W, Kudo Y, Naka K, Fujimoto J, Ue T, Yokozaki H and Tahara E: Expression of CD44 containing variant exon 9 (CD44v9) in gastric adenomas and adenocarcinomas: Relation to the proliferation and progression. Int J Oncol 12:1253-1258, 1998
  109. Ue T, Yokozaki H, Kagai K, Higashikawa K, Yasui W, Sugiyama M, Tahara E and Ishikawa T: Reduced expression of the CD44 variant exons in oral squamous cell carcinoma and its relationship to metastasis. J Oral Pathol Med 27:197-201, 1998
  110. Yamamoto S, Yasui W, Kitadai Y, Yokozaki H, Haruma K, Kajiyama G and Tahara E: Expression of vascular endothelial growth factor in human gastric carcinomas. Pathol Int 48:499-506, 1998
  111. Hiyama T, Yokozaki H, Shimamoto F, Haruma K, Yasui W, Kajiyama G and Tahara E: Frequent p53 gene mutations in serrated adenomas of the colorectum. J Pathol 186:131-139, 1998
  112. Yasui W, Tahara H, Tahara E, Fujimoto J, Nakayama J, Ishikawa F, Ide T and Tahara E: Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas. Jpn J Cancer Res 89:1099-1103, 1998
  113. Hiyama T, Yokozaki H, Kitadai Y, Tahara Ej, Tahara H, Ide T, Haruma K, Yasui W, Kajiyama G and Tahara E: In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions. Jpn J Cancer Res 89:1187-1194, 1998
  114. Kudo Y, Takata T, Yasui W, Ogawa I, Miyauchi M, Takekoshi T, Tahara E and Nikai H: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior of oral squamous cell carcinomas. Cancer 83:2447-2455, 1998
  115. Sarac E, Ayhan A, Ertoy D, Tuncer ZS, Yasui W, Tahara E and Ayhan A: nm23 expression in carcinoma of the uterine cervix. Eur J Gynaecol Oncol 19:312-315, 1998
  116. Ayhan A, Tuncer ZS, Ruacan S, Ayhan A, Yasui W and Tahara E: Abnormal expression of cripto and p53 protein in endometrial carcinoma and its precursor lesions. Eur J Gynaecol Oncol 19:316-318, 1998
  117. Ayhan A, Usunutun A, Ozen H, Yasui W and Tahara E: nm23 protein expression in renal cell tumors: the role of the cell type. Oncol Reports 5:979-983, 1998
  118. Kiriu H, Yokozaki H, Yasui W, Ito K and Tahara E: Microsatellite instability associated with primary head and neck cancers and secondary esophageal cancers. Jpn J Clinical Oncol 28:733-739, 1998
  119. Shitara Y, Yokozaki H, Yasui W, Takenoshita S, Kuwano H, Nagamachi Y and Tahara E: No mutations of the Smad2 gene in human sporadic gastric carcinomas. Jpn J Clin Oncol 29:3-7, 1999
  120. Tahara H, Yasui W, Tahara E, Fujimoto J, Ito K, Tamai K, Nakayama J, Ishikawa F, Tahara E and Ide T: Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumors and non-tumor tissue sections. Oncogene 18:1561-1568, 1999
  121. Naka K, Yokozaki H, Yasui W, Tahara H, Tahara Ej and Tahara E: Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell lines. Biochem Biophys Res Commun 255:753-758, 1999
  122. Suzuki T, Yasui W, Yokozaki H, Naka K, Ishikawa T and Tahara E: Expression of the E2F family in human gastrointestinal carcinomas. Int J Cancer 81:535-538, 1999
  123. Sato S, Yokozaki H, Yasui W, Nikai H and Tahara E: Silencing of the CD44 gene by CpG methylation in a human gastric carcinoma cell line. Jpn J Cancer Res 90:485-489, 1999
  124. Yasui W, Tahara Ej, Tahara H, Fujimoto J, Naka K, Nakayama J, Ishikawa F, Ide T and Tahara E: Immunohistochemical detection of human telomerase reverse transcriptase in normal mucosa and precancerous lesions of the stomach. Jpn J Cancer Res 90:589-595, 1999
  125. Hiyama T, Yokozaki H, Kitadai Y, Haruma K, Yasui W, Kajiyama G and Tahara E: Overexpression of human telomerase RNA is an early event in oesophageal carcinogenesis. Virchows Archiv 434:483-487, 1999
  126. Yasui W, Naka K, Suzuki T, Fujimoto J, Hayashi K, Matsutani N, Yokozaki H and Tahara E: Expression of p27Kip1, cyclin E and E2F-1 in primary and metastatic tumors of gastric carcinoma. Oncology Reports 6:983-987, 1999
  127. Yokozaki H, Shitara Y, Fujimoto J, Hiyama T, Yasui W and Tahara E: Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype. Int J Cancer 83:192-196, 1999
  128. Kitadai Y, Takahashi Y, Haruma K, Naka K, Sumii K, Yokozaki H, Yasui W, Ohmoto Y, Mukaida N, Kajiyama G, Fidler IJ and Tahara E: Evidence for the causal role of IL-8 in angiogenesis and tumorigenicity of human gastric carcinoma cells. Br J Cancer 81:647-653, 1999
  129. Arber N, Hibshoosh H, Yasui W, Neugut AI, Hibshoosh A, Yao Y, Sgambato A, Yamamoto H, Shapira I, Rosenman D, Fabian I, Weinstein B, Tahara E and Holt PR: Abnormalities in the expression cell cycle related proteins in tumors of the small bowel. Cancer Epidemiol Biomarkers Prev 8:1101-1105, 1999
  130. Nakamura Y, Tahara Ej, Tahara H, Yasui W, Tahara E and Ide T: Quantitative reevaluation of telomerase activity in cancerous and non-cancerous gastrointestinal tissues. Mol Carcinogenesis 26:312-320, 1999
  131. Ito R, Yasui W, Ogawa Y, Tahara E and Ijuin N: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 in oral malignant tumors. Pathobiol 67:169-173, 1999
  132. Yasui W, Fujimoto J, Suzuki T, Ono S, Naka K, Yokozaki H and Tahara E: Expression of cell cycle regulating transcription factor E2F-1 in colorectal carcinomas. Pathobiol 67:174-179, 1999